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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
12.42
Human Site:
Y333
Identified Species:
24.85
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
Y333
E
S
I
Q
E
G
K
Y
E
F
P
D
K
D
W
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
Y321
E
S
I
Q
E
G
K
Y
E
F
P
D
K
D
W
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
L297
I
S
S
E
A
K
D
L
I
S
K
L
L
V
R
Dog
Lupus familis
XP_539626
415
46182
I298
S
P
E
A
K
D
L
I
S
K
L
L
V
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
K307
A
H
I
S
N
E
A
K
D
L
I
S
K
L
L
Rat
Rattus norvegicus
Q4G050
413
46195
K295
A
H
I
S
T
E
A
K
D
L
I
S
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
Y375
E
S
I
Q
E
G
K
Y
E
F
P
D
K
D
W
Frog
Xenopus laevis
Q9YGW0
418
46898
L301
A
K
D
L
I
S
K
L
L
V
R
D
A
K
E
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
Y339
E
R
I
Q
E
G
K
Y
E
F
S
D
G
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
D640
E
Q
Q
Q
R
V
D
D
K
F
G
E
E
E
F
Honey Bee
Apis mellifera
XP_395927
516
58135
V348
I
N
P
G
P
S
S
V
E
N
T
E
K
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
Q389
L
L
V
R
D
A
K
Q
R
Y
T
A
G
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
100
6.6
0
N.A.
13.3
13.3
N.A.
N.A.
100
13.3
73.3
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
20
20
N.A.
N.A.
100
13.3
73.3
N.A.
53.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
9
9
9
17
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
9
17
9
17
0
0
42
0
25
9
% D
% Glu:
42
0
9
9
34
17
0
0
42
0
0
17
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
42
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
34
0
0
0
0
9
0
17
0
0
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
50
0
9
0
0
9
9
0
17
0
0
0
0
% I
% Lys:
0
9
0
0
9
9
50
17
9
9
9
0
50
9
0
% K
% Leu:
9
9
0
9
0
0
9
17
9
17
9
17
9
17
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
9
0
9
0
0
0
0
0
25
0
0
0
0
% P
% Gln:
0
9
9
42
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
9
0
0
0
9
0
9
0
0
9
9
% R
% Ser:
9
34
9
17
0
17
9
0
9
9
9
17
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
9
0
0
9
0
9
0
9
0
0
9
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% W
% Tyr:
0
0
0
0
0
0
0
34
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _